Research Article

High Expression of Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 Predicts Poor Prognosis in Head and Neck Squamous Cell Carcinoma

Figure 1

Immunohistochemical staining for LETM1 protein in HNSCC and normal squamous epithelia. (a) LETM1 protein is negative in normal squamous epithelial cells. ((b)–(d)) LETM1 protein showed strongly cytoplasmic positive signals in HNSCC with well (b), moderate (c), and poor (d) differentiation. (e) LETM1 protein is strongly positive in HNSCC with lymph node metastasis. (f) LETM1 protein is negative in HNSCC with no metastasis. (Original magnification, (a)–(f), ).
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