High Expression of Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 Predicts Poor Prognosis in Head and Neck Squamous Cell Carcinoma

Table 3

Univariate survival analyses (Cox regression model) of various factors in patients with HNSCC.

Factors	Disease-free survival	𝑃 value	Overall survival	𝑃 value
	Hazard ratio (95% CI)		Hazard ratio (95% CI)
Gender	1.135 (0.834–1.545)	0.421	1.049 (0.771–1.428)	0.760
Age	1.223 (0.904–1.655)	0.191	1.221 (0.902–1.651)	0.196
Primary site	0.931 (0.806–1.075)	0.328	0.946 (0.820–1.092)	0.449
differentiation	1.412 (1.154–1.726)	0.001**	1.342 (1.095–1.644)	0.005**
pT	1.759 (1.295–2.390)	0.235	1.366 (1.012–1.846)	0.146
Lymph node	1.108 (0.786–1.563)	0.558	1.068 (0.758–1.507)	0.706
Stage	2.211 (1.581–3.092)	0.000**	1.675 (1.205–2.239)	0.002**
Alcohol use	1.314 (0.964–1.791)	0.085	1.135 (0.979–1.821)	0.068
Smoking	1.243 (0.920–1.679)	0.157	1.127 (0.835–1.521)	0.436
Chemoradiotherapy	2.367 (1.713–3.273)	0.000**	1.948 (1.418–2.675)	0.000**
LETM1	1.628 (1.192–2.224)	0.002**	1.478 (1.083–2.017)	0.014*