Research Article

Clinical Correlates of Hachinski Ischemic Score and Vascular Factors in Cognitive Function of Elderly

Table 4

Relationship between HIS and cognitive function and HIS and vascular factors in two groups divided by HIS score.

HIS 0~2 ()HIS 3~12 ()P value

Age, yr (mean ± SD)*73.92 ± 5.4074.31 ± 5.720.388
Male (%)63 (29.0)49 (37.4)0.105
Family history of dementia (%)6 (2.8)13 (9.9)0.004
Family history of stroke (%)37 (17.1)31 (23.7)0.132
Diabetes mellitus (%)34 (15.7)17 (13.0)0.492
Hypertension (%)73 (33.6)54 (41.2)0.155
Hyperlipidemia (%)11 (5.1)7 (5.3)0.911
Cardiac disease (%)25 (11.5)29 (22.1)0.008
Stroke (%)5 (2.3)15 (11.5)<0.001
K-MMSE, mean ± SD*23.59 ± 4.4222.43 ± 5.130.025
CDR, mean ± SD*0.20 ± 0.260.29 ± 0.310.008
CDR-SB, mean ± SD*0.43 ± 0.680.79 ± 1.370.006
BMI, mean ± SD*22.73 ± 3.3123.10 ± 2.980.246

HIS: Hachinski ischemic score; SD: standard deviation; K-MMSE, Korean version of Mini-Mental State Examination; CDR, Clinical Dementia Rating; SB, Sum of Boxes; BMI, body mass index. *statistically significant with by independent -test and Chi-square test.