Acute In Vivo Response to an Alternative Implant for Urogynecology
Figure 4
Assessment of the acute host response against the implanted samples. Representative light microscopy image of sections of abdominal wall of female Sprague-Dawley rats after 3 and 7 days of implantation of PLA scaffold on top, previously cultured with and without (control) rat or human ADSCs in DMEM medium for 2 weeks; following immunohistochemistry for anti-CD68 antibody (a) or anti-PECAM-1 antibody (b). (a) Macrophages surrounding individual PLA fibres are identified by (↑). (b) Endothelial cells stained for PECAM-1 around blood vessels are identified by (↑). Scale bars of 0.1 mm. (S) Sample; (F) Fascia.
