Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014 (2014), Article ID 867131, 10 pages
http://dx.doi.org/10.1155/2014/867131
Research Article

Increased Stem Cell Marker Expressions during the Peri-Implantation Period in the Rat Endometrium: Constructive Role of Exogenous Zinc and/or Progesterone

1Department of Obstetrics and Gynecology, Tepecik Training and Research Hospital, 35170 Izmir, Turkey
2Department of Histology and Embryology, Medicine Faculty, Ege University, 35040 Izmir, Turkey
3Department of Obstetrics and Gynecology, Medicine Faculty, Ege University, 35040 Izmir, Turkey
4Department of Biochemistry, Medicine Faculty, Ege University, 35040 Izmir, Turkey

Received 27 February 2014; Revised 5 May 2014; Accepted 6 May 2014; Published 26 May 2014

Academic Editor: Dong-Wook Han

Copyright © 2014 Cagdas Sahin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. Speroff and M. A. Fritz, Clinical Gynecologic Endocrinology and Infertility, Lippincott Williams & Wilkins Press, Philadelphia, Pa, USA, 7th edition, 2005.
  2. D. J. Bloor, A. D. Metcalfe, A. Rutherford, D. R. Brison, and S. J. Kimber, “Expression of cell adhesion molecules during human preimplantation embryo development,” Molecular Human Reproduction, vol. 8, no. 3, pp. 237–245, 2002. View at Google Scholar · View at Scopus
  3. B. A. Lessey, L. Damjanovich, C. Coutifaris, A. Castelbaum, S. M. Albeida, and C. A. Buck, “Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle,” The Journal of Clinical Investigation, vol. 90, no. 1, pp. 188–195, 1992. View at Google Scholar · View at Scopus
  4. S. Campbell, H. R. Swann, and M. W. Seif, “Cell adhesion molecules on the oocyte and preimplantation human embryo,” Human Reproduction, vol. 10, no. 6, pp. 1571–1578, 1995. View at Google Scholar
  5. K. Kühn and J. Eble, “The structural bases of integrin-ligand interactions,” Trends in Cell Biology, vol. 4, no. 7, pp. 256–261, 1994. View at Publisher · View at Google Scholar · View at Scopus
  6. C. E. Gargett, “Uterine stem cells: what is the evidence?” Human Reproduction Update, vol. 13, no. 1, pp. 87–101, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. B. A. Lessey, “Two pathways of progesterone action in the human endometrium: implications for implantation and contraception,” Steroids, vol. 68, no. 10–13, pp. 809–815, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. L. P. Freedman, “Anatomy of the steroid receptor zinc finger region,” Endocrine Reviews, vol. 13, no. 2, pp. 129–145, 1992. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Favier, P. Faure, A. M. Roussel, C. Coudray, D. Blache, and A. Favier, “Zinc deficiency and dietary folate metabolism in pregnant rats,” Journal of Trace Elements and Electrolytes in Health and Disease, vol. 7, no. 1, pp. 19–24, 1993. View at Google Scholar · View at Scopus
  10. P. A. Rogers and B. J. Gannon, “The vascular and microvascular anatomy of the rat uterus during the oestrous cycle,” The Australian Journal of Experimental Biology and Medical Science, vol. 59, part 6, pp. 667–679, 1981. View at Google Scholar
  11. B. A. Lessey, A. J. Castelbaum, C. A. Buck, Y. Lei, C. W. Yowell, and J. Sun, “Further characterization of endometrial integrins during the menstrual cycle and in pregnancy,” Fertility and Sterility, vol. 62, no. 3, pp. 497–506, 1994. View at Google Scholar · View at Scopus
  12. B. A. Lessey, Y. Gui, K. B. C. Apparao, S. L. Young, and J. Mulholland, “Regulated expression of heparin-binding EGF-like growth factor (HB-EGF) in the human endometrium: a potential paracrine role during implantation,” Molecular Reproduction and Development, vol. 62, no. 4, pp. 446–455, 2002. View at Publisher · View at Google Scholar · View at Scopus
  13. A. E. Favier, “The role of zinc in reproduction: hormonal mechanisms,” Biological Trace Element Research, vol. 32, pp. 363–382, 1992. View at Google Scholar · View at Scopus
  14. P. C. Brooks, S. Stromblad, and L. C. Sanders, “Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3,” Cell, vol. 85, no. 5, pp. 683–693, 1996. View at Publisher · View at Google Scholar
  15. D. Shah and H. P. Sachdev, “Effect of gestational zinc deficiency on pregnancy outcomes: summary of observation studies and zinc supplementation trials,” British Journal of Nutrition, vol. 85, supplement 2, pp. S101–S108, 2001. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Y. Uriu-Adams and C. L. Keen, “Zinc and reproduction: effects of zinc deficiency on prenatal and early postnatal development,” Birth Defects Research B: Developmental and Reproductive Toxicology, vol. 89, no. 4, pp. 313–325, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. X. Tian and F. J. Diaz, “Acute dietary zinc deficiency before conception compromises oocyte epigenetic programming and disrupts embryonic development: preconception zinc and oocyte quality,” Developmental Biology, vol. 376, no. 1, pp. 51–61, 2013. View at Publisher · View at Google Scholar
  18. A. M. Kim, M. L. Bernhardt, B. Y. Kong et al., “Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs,” ACS Chemical Biology, vol. 6, no. 7, pp. 716–723, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. A. T. Khan, T. C. Graham, L. Ogden et al., “A two-generational reproductive toxicity study of zinc in rats,” Journal of Environmental Science and Health B, vol. 42, no. 4, pp. 403–415, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. B. Zhu, L. Liu, D. L. Li, F. Ling, and G. X. Wang, “Developmental toxicity in rare minnow (Gobiocypris rarus) embryos exposed to Cu, Zn and Cd,” Ecotoxicology and Environmental Safety, vol. 104, pp. 269–277, 2014. View at Publisher · View at Google Scholar
  21. M. J. Salgueiro, M. B. Zubillaga, A. E. Lysionek et al., “Bioavailability, biodistribution, and toxicity of BioZn-AAS1: a new source. Comparative studies in rats,” Nutrition, vol. 16, no. 9, pp. 762–766, 2000. View at Publisher · View at Google Scholar · View at Scopus
  22. F. O. Johnson, E. T. Gilbreath, L. Ogden, T. C. Graham, and S. Gorham, “Reproductive and developmental toxicities of zinc supplemented rats,” Reproductive Toxicology, vol. 31, no. 2, pp. 134–143, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. Agency for Toxic Substances and Disease Registry (ATSDR), Toxicology Profile for Zinc, Public Health Service, US Department of Health and Human Services, Atlanta, Ga, USA, 1995.
  24. C. E. Eckfeldt, E. M. Mendenhall, and C. M. Verfaillie, “The molecular repertoire of the “almighty” stem cell,” Nature Reviews Molecular Cell Biology, vol. 6, no. 9, pp. 726–737, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. L. Li and T. Xie, “Stem cell niche: structure and function,” Annual Review of Cell and Developmental Biology, vol. 21, pp. 605–631, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. C. E. Gargett, “Identification and characterisation of human endometrial stem/progenitor cells,” Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 46, no. 3, pp. 250–253, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Kauma, T. Huff, G. Krystal, J. Ryan, P. Takacs, and T. Turner, “The expression of stem cell factor and its receptor, c-kit in human endometrium and placental tissues during pregnancy,” The Journal of Clinical Endocrinology & Metabolism, vol. 81, no. 3, pp. 1261–1266, 1996. View at Google Scholar
  28. H. Niwa, J. Miyazaki, and A. G. Smith, “Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells,” Nature Genetics, vol. 24, no. 4, pp. 372–376, 2000. View at Publisher · View at Google Scholar · View at Scopus
  29. A. A. Avilion, S. K. Nicolis, L. H. Pevny, L. Perez, N. Vivian, and R. Lovell-Badge, “Multipotent cell lineages in early mouse development depend on SOX2 function,” Genes & Development, vol. 17, no. 1, pp. 126–140, 2003. View at Publisher · View at Google Scholar · View at Scopus
  30. T. A. Baudino, C. McKay, H. Pendeville-Samain et al., “c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression,” Genes & Development, vol. 16, no. 19, pp. 2530–2543, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. J. P. Katz, N. Perreault, B. G. Goldstein et al., “The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon,” Development, vol. 129, no. 11, pp. 2619–2628, 2002. View at Google Scholar · View at Scopus
  32. A. Barash, N. Dekel, S. Fieldust, I. Segal, E. Schechtman, and I. Granot, “Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization,” Fertility and Sterility, vol. 79, no. 6, pp. 1317–1322, 2003. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Raziel, M. Schachter, D. Strassburger, O. Bern, R. Ron-El, and S. Friedler, “Favorable influence of local injury to the endometrium in intracytoplasmic sperm injection patients with high-order implantation failure,” Fertility and Sterility, vol. 87, no. 1, pp. 198–201, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. L. Zhou, R. Li, R. Wang, H.-X. Huang, and K. Zhong, “Local injury to the endometrium in controlled ovarian hyperstimulation cycles improves implantation rates,” Fertility and Sterility, vol. 89, no. 5, pp. 1166–1176, 2008. View at Publisher · View at Google Scholar · View at Scopus
  35. H. S. Taylor, “Endometrial cells derived from donor stem cells in bone marrow transplant recipients,” The Journal of the American Medical Association, vol. 292, no. 1, pp. 81–85, 2004. View at Publisher · View at Google Scholar · View at Scopus
  36. H. Du and H. S. Taylor, “Contribution of bone marrow-derived stem cells to endometrium and endometriosis,” Stem Cells, vol. 25, no. 8, pp. 2082–2086, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. Z.-X. Wang, C. H. Teh, C. M. Chan et al., “The transcription factor Zfp281 controls embryonic stem cell pluripotency by direct activation and repression of target genes,” Stem Cells, vol. 26, no. 11, pp. 2791–2799, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. Z.-X. Wang, C. H. Teh, J. L. Kueh, T. Lufkin, P. Robson, and L. W. Stanton, “Oct4 and Sox2 directly regulate expression of another pluripotency transcription factor, Zfp206, in embryonic stem cells,” The Journal of Biological Chemistry, vol. 282, no. 17, pp. 12822–12830, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. F. Chimienti, M. Aouffen, A. Favier, and M. Seve, “Zinc homeostasis-regulating proteins: new drug targets for triggering cell fate,” Current Drug Targets, vol. 4, no. 4, pp. 323–338, 2003. View at Publisher · View at Google Scholar · View at Scopus
  40. Y. C. Hung, P. G. Satyaswaroop, and S. Tabibzadeh, “The female reproductive system: cell lines from tumors of the human ovary and uterus,” in Atlas of Human Tumor Cell Lines, pp. 359–385, Elsevier, 1994. View at Google Scholar