Research Article

A Mathematical Model of Skeletal Muscle Disease and Immune Response in the mdx Mouse

Figure 9

The effect of varying the parameter , while fixing all other parameters, on the trajectories of fibers. As the value of increases, the percentage of damaged fibers decreases (panel (a)) while the percentage of normal (c) fiber increases and eventually reaches 100% (disease-free state), when is optimal. Beyond that, however, an oscillatory behaviour appears, where the damage is persistent and most of the tissue is regenerating (b).
871810.fig.009a
(a)
871810.fig.009b
(b)
871810.fig.009c
(c)