A Mathematical Model of Skeletal Muscle Disease and Immune Response in the mdx Mouse

Table 2

Some of the model parameters (column 1), their estimated values (column 2), and, for each parameter, a lower (column 3) and an upper (column 4) bound. To study the sensitivity of the model to a given parameter, we varied the value of that parameter within its range above, and qualitatively examined the resulting dynamics.

Parameter	Value	Min	Max
𝑘1	0.0324139	0.0160773	0.0643092
𝑑𝐻	0.83355	0.416775	1.6671
𝑘2	0.115375	0.0577452	0.230981
𝑑𝐶	1.61511	0.807555	3.23022
𝑘3	0.766576	0.381371	1.52549
𝑑𝑀	0.781155	0.390577	1.56231
𝑘4	0.123848	0.061924	0.247696
𝑘5	4.09948×10^−3	2.04974×10^−3	8.19896×10^−3
𝑘6	3.23097×10^−4	1.61548×10^−4	6.46194×10^−4
𝑑𝐷	1.34671	0.673355	2.69342