New Progress in Angiogenesis Therapy of Cardiovascular Disease by Ultrasound Targeted Microbubble Destruction
Figure 5
Representative microscopic images of angiogenesis after UTMD mediated TB4 treatment (scale bar = 150 mm). ((a)–(c)) The top panels are stained antibodies against smooth muscle a-actin (SMaA) (red) and nucleus (blue). Groups from left to right are, respectively, normal control, DsRed control, and UTMD-TB4 treated. An increase in SMaA was observed in the UTMD-TB4 treatment group, being consistent with coronary arteriogenesis response. ((d)–(f)) The middle panels are similar except the antibody is against CD31. Adapted from [38].
