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BioMed Research International
Volume 2014, Article ID 873010, 12 pages
http://dx.doi.org/10.1155/2014/873010
Research Article

Potential Smoothened Inhibitor from Traditional Chinese Medicine against the Disease of Diabetes, Obesity, and Cancer

1School of Pharmacy, China Medical University, Taichung 40402, Taiwan
2School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan
3Department of Acupuncture, China Medical University Hospital, Taichung, Taiwan
4Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, Taiwan
5Department of Biomedical Informatics, Asia University, Taichung 41354, Taiwan
6School of Medicine, College of Medicine, China Medical University, Taichung 40402, Taiwan
7Human Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan

Received 14 February 2014; Accepted 15 February 2014; Published 1 July 2014

Academic Editor: Chung Y. Hsu

Copyright © 2014 Kuan-Chung Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

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  • Duomao Lin, Jun Ma, Yanyan Xue, and Zhaoqi Wang, “Penehyclidine Hydrochloride Preconditioning Provides Cardioprotection in a Rat Model of Myocardial Ischemia/Reperfusion Injury,” Plos One, vol. 10, no. 12, 2015. View at Publisher · View at Google Scholar
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  • Betty Yuen-Kwan Law, Xiao-Jun Yao, Liang Liu, Vincent Kam-Wai Wong, Xi Chen, Su Wei Xu, and Elaine Lai-Han Leung, “Advanced research technology for discovery of new effective compounds from Chinese herbal medicine and their molecular targets,” Pharmacological Research, vol. 111, pp. 546–555, 2016. View at Publisher · View at Google Scholar
  • Yu-Hui Tseng, Po-Hsiang Chuang, Yu-Ren Huang, and Cheng-Lung Chen, “Computational Investigation into the Interactions of Traditional Chinese Medicine Molecules of WenQingYin with GluR2,” International Journal of Molecular Sciences, vol. 18, no. 7, pp. 1443, 2017. View at Publisher · View at Google Scholar
  • Noopur Sinha, Ram Rup Sarkar, and Saikat Chowdhury, “Deciphering structural stability and binding mechanisms of potential antagonists with smoothened protein,” Journal of Biomolecular Structure and Dynamics, vol. 36, no. 11, pp. 2917–2937, 2018. View at Publisher · View at Google Scholar