Butylidenephthalide Blocks Potassium Channels and Enhances Basal Tension in Isolated Guinea-Pig Trachea

Figure 4

Inhibitory effects of atropine, FPL 55712, or pyrilamine 1 μM (a), as well as pyrilamine 10 μM or methysergide (b) and α-chymotrypsin (c) on cumulative butylidenephthalide- (Bdph-) induced contraction of baseline tension in isolated guinea-pig trachea. All values are shown as mean ± SEM, and 𝑛 is the number of experiments. There is no significant difference between test and respective control.

(a)

(b)

(c)