Butylidenephthalide Blocks Potassium Channels and Enhances Basal Tension in Isolated Guinea-Pig Trachea

Figure 8

Influences of tetraethylamine (TEA, (a)) and 4-aminopyridine (4-AP, (b)) to the antagonistic effect of butylidenephthalide (Bdph) on cumulative cromakalim-induced relaxant response to histamine-induced precontraction in isolated guinea-pig trachea. All values are shown as mean ± SEM, and 𝑛 is the number of experiments. ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 compared to its vehicle.

(a)

(b)