Determinants of Disability in Multiple Sclerosis: An Immunological and MRI Study

Table 4

Percentages of MBP-stimulated cytokine producing blood cells from historical controls and all MS patients.

Cell type	Historical controls	All MS	All MS versus historical controls
CD4+IL17+	0.0 (0-0)	0.04 (0–0.08)	<0.0001
CD4+IFN𝛾+	0.01 (0–0.08)	0.01 (0–0.03)	ns
CD14+IL12p35+	0.0 (0-1)	0.13 (0–2.01)	ns
CD14+IL6+	0.0 (0-1)	1.9 (0–5.5)	ns
CD4+IL13+	0.05 (0–0.1)	0.12 (0.01–0.16)	0.003
CD4+IL25+	0.13 (0–0.15)	0.33 (0.1–0.5)	<0.0001
CD14+IL10+	12.0 (0.03–26.8)	12.1 (0.17–21.3)	ns
CD14+TGF𝛽+	0.0 (0-1)	1.65 (0–6.25)	ns
CD4+BDNF+	0.07 (0–0.43)	0.72 (0–2.8)	<0.0001

Data are reported as median values (interquartile ranges).
𝑃 values from group comparisons (𝑡-test) are reported; ns: not significant.