BioMed Research International / 2014 / Article / Tab 1

Research Article

Acute and Subacute Toxicity In Vivo of Thermal-Sprayed Silver Containing Hydroxyapatite Coating in Rat Tibia

Table 1

Laboratory parameters in the acute phase (2–4 days postoperatively).

Time after treatment Implant coating GOT (IU/L) GPT (IU/L) LDH (IU/L) Creatinine (mg/dL) BUN (mg/dL)

Control
2 days HA
2% AgHA
50% AgHA
3 days HA
2% AgHA
50% AgHA
4 days HA
2% AgHA
50% AgHA

Five 10-week-old male Sprague-Dawley rats with no treatment were used as controls. No significant differences were seen between the control group and all comparators.
GOT: glutamic-oxaloacetic transaminase; GPT: glutamic-pyruvic transaminase; LDH: lactate dehydrogenase; BUN: blood urea nitrogen.