Clinical Nonlinear Laser Imaging of Human Skin: A Review

Figure 4

SHG imaging of collagen after laser resurfacing. SHG images of human dermis taken at 80 μm, 130 μm, and 180 μm from skin surface on the inner forearm of healthy volunteers before and 40 days after microablative fractional laser resurfacing treatment. On the top, representative images of Group I (age < 35 years) taken before ((a), (b), and (c)) and 40 days after ((d), (e), and (f)) the treatment. In the middle, representative images of Group II (35 years < age < 60 years) taken before ((g), (h), and (i)) and 40 days after ((j), (k), and (l)) treatment. At the bottom, representative images of Group III (age > 60 years) taken before ((m), (n), and (o)) and 40 days after ((p), (q), and (r)) treatment. Field of view: 400 μm. Scale bars: 40 μm. Figure modified from [38].