Research Article
Cardiac Troponin T (TNNT2) Mutations in Chinese Dilated Cardiomyopathy Patients
Table 2
Mutations in TNNT2 in DCM patients.
| | Markers | Exon/intron | Location of nucleotide change | Amino acid change | Number of patients | Gender | Age at diagnosis (years) | Family history | LVEDD (mm) | LVEF (%) |
| | c. | Intron 6 | 201337183 C>T | Noncoding | 1 | Male | 37 | No | 82 | 18 | | c. | Intron 6 | 201336948 C>T | Noncoding | 1 | Male | 30 | No | 81 | 31 | | c. | Intron 7 | 201336387 A>C | Noncoding | 1 | Male | 59 | Suspensive coronary heart disease | 60 | 45 | | c.252 | Exon 9 | 201334780 G>T | Leu 84 Phe | 1 | Male | 43 | Suspensive
coronary heart disease | 60 | 31 | | c. | Intron 9 | 201334595 G>A | Noncoding | 1 | Male | 45 | No | 58 | 40 | | c. | Intron 10 | 201333948 A>G | Noncoding | 1 | Male | 62 | Suspensive cardiovascular disease | 80 | 36 |
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Note: LVEDD: left ventricular end-diastolic diameter; LVEF: left ventricular ejection fraction.
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