Review Article

# Estimating Glomerular Filtration Rate in Older People

## Table 2

Equations for estimating renal function.
 Cockcroft and Gault [69] eCCr = (140−age) × weight in kg/(72 × Scr), ×0.85 in females Six-variable MDRD [71] 170 * [Scr]−0.999 * age −0.176 * BUN −0.170 * serum albumin 0.318, *0.762 in females, *1.180 if black Four-variable MDRD [71] 186.3 × (Scr)−1.154  × (age)−0.203 , ×0.742 in females, ×1.212 if black CKD-EPI (creatinine) [77] Female (Scr ≤ 0.7), eGFR = 144 × (Scr/0.7)−0.329  × (0.993)Age    (Scr > 0.7), eGFR = 144 × (Scr/0.7)−1.209  × (0.993)Age  Male (Scr ≤ 0.9), eGFR = 141 × (Scr/0.9)−0.411  × (0.993)Age   (Scr > 0.9), eGFR = 141 × (Scr/0.9)−1.209  × (0.993)Age CKD-EPI (cystatin C) [80] (Scys ≤ 0.8), eGFR = 133 × (Scys/0.8)−0.499  × 0.996Age   ×0.932 if female  (Scys > 0.8), eGFR = 133 × (Scys/0.8)−1.328  × 0.996Age   ×0.932 if female CKD-EPI (cystatin C-creatinine) [80] Female (Scr ≤ 0.7) (Scys ≤ 0.8), eGFR = 130 × (Scr/0.7)−0.248  × (Scys/0.8)−0.375  × 0.995Age   ×1.08 if black       (Scr ≤ 0.7) (Scys > 0.8), eGFR = 130 × (Scr/0.7)−0.248  × (Scys/0.8)−0.711  × 0.995Age   ×1.08 if black Female (Scr > 0.7) (Scys ≤ 0.8), eGFR = 130 × (Scr/0.7)−0.601  × (Scys/0.8)−0.375  × 0.995Age   ×1.08 if black      (Scr > 0.7) (Scys > 0.8), eGFR = 130 × (Scr/0.7)−0.601  × (Scys/0.8)−0.711  × 0.995Age   ×1.08 if black Male (Scr ≤ 0.9) (Scys ≤ 0.8), eGFR = 135 × (Scr/0.9)−0.207  × (Scys/0.8)−0.375  × 0.995Age   ×1.08 if black      (Scr ≤ 0.9) (Scys > 0.8), eGFR = 135 × (Scr/0.9)−0.207  × (Scys/0.8)−0.711  × 0.995Age   ×1.08 if black Male (Scr > 0.9) (Scys ≤ 0.8), eGFR = 135 × (Scr/0.9)−0.601  × (Scys/0.8)−0.375  × 0.995Age   ×1.08 if black     (Scr > 0.9) (Scys > 0.8), eGFR = 135 × (Scr/0.9)−0.601  × (Scys/0.8)−0.711  × 0.995Age   ×1.08 if black BIS1 [81] 3736 × creatinine−0.87  × age−0.95  × 0.82 (if female) BIS2 [81] 767 × cystatin C−0.61  × creatinine−0.40  × age−0.57  × 0.87 (if female)
eCCr: estimated creatinine clearance; Scr: serum creatinine; BUN: blood urea nitrogen; Scys: serum cystatin C; MDRD: Modification of Diet in Renal Disease; CKD-EPI: Chronic Kidney Disease Epidemiological Collaboration; BIS: Berlin Initiative Study.

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