Gradually Increased Training Intensity Benefits Rehabilitation Outcome after Stroke by BDNF Upregulation and Stress Suppression

<table>Behavioral scores over the seven-day intervention. A higher behavioral score indicates better motor function. <svg height="17.825001" id="M40" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 7.7375002 17.825001" width="7.7375002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>: significant difference observed via 2-way repeated measures ANOVA with the score on D1 as covariate when comparing GIG to the other three groups. <sup>#, +</sup>: significant difference observed via 2-way repeated measures ANOVA with the score on D1 as covariate when comparing LG and HG to CG, respectively. From D3 to D7, rats in GIG scored significantly higher for behavioral score compared to LG, HG, and CG, while rats in LG and HG showed better motor function on D6 and D7 compared to CG. Results suggested that gradually increased training intensity can facilitate motor function recovery during the subacute stroke period.</table>

BioMed Research International

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Figure 3

Figure 3: Gradually Increased Training Intensity Benefits Rehabilitation Outcome after Stroke by BDNF Upregulation and Stress Suppression 