Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains
Table 6
Minimum inhibitory concentrations (MIC) for antibiotic susceptibility of Lactobacillus strains.
Antibiotic [MIC (g/mL)]
Strain
Ampicillin
Gentamicin
Kanamycin
Streptomycin
Erythromycin
Clindamycin
Tetracycline
Chloramphenicol
Breakpoint*
4
16
64
64
1
1
8
4
L. casei Shirota**
<0.25
<8
<64
<32
<1
<0.063
<1
<4
L. acidophilus HM1
<0.063
<0.125
<0.125
<0.5
<0.063
<0.063
<0.063
<0.063
L. fermentum HM2
<0.063
<4
<8
<8
<0.5
<0.063
<1
<1
L. fermentum HM3
<0.063
<4
<8
<4
<0.5
<0.063
<1
<1
L. buchneri FG1
<0.5
<2
<8
<8
<0.25
<0.063
<2
<1
L. buchneri FD1
<0.5
<4
<8
<8
<0.25
<0.063
<2
<1
L. buchneri FD2
<0.5
<2
<8
<2
<0.125
<0.063
<2
<1
L. casei BF1
<0.125
<8
<8
<4
<0.125
<0.063
<0.5
<0.25
L. casei BF2
<0.5
<4
<8
<4
<0.125
<0.25
<1
<0.5
L. casei BF3
<0.5
<8
<8
<4
<0.125
<0.125
<1
<0.5
Values are provided by EFSA [22] for facultative heterofermentative Lactobacillus strains; according to EFSA, susceptibility testing of heterofermentative Lactobacillus strains against vancomycin is not required. Reference strain.