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BioMed Research International

Volume 2014 (2014), Article ID 927304, 1 page

High-Intensity Physical Training in the Treatment of Chronic Diseases and Disorders

1National Research Centre for the Working Environment, Lersø Parkallé 105, DK-2100 Copenhagen O, Denmark

2Memorial University of Newfoundland, St. John's, NL, Canada A1B 3X9

3Schulthess Clinic, 8008 Zurich, Switzerland

4CUNY Lehman College, New York, NY 10065, USA

Received 13 April 2014; Accepted 13 April 2014; Published 5 May 2014

Copyright © 2014 Lars L. Andersen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Chronic diseases, such as diabetes, stroke, heart disease, cancer, and chronic respiratory diseases, are the leading cause of mortality worldwide, accounting for two-thirds of all deaths. Musculoskeletal disorders, such as osteoarthritis, rheumatoid arthritis, osteoporosis, neck pain, and low back pain, are associated with disability, loss of productivity at work, and sick leave. Neurological disorders can affect both physical and mental function and lead to major disability and suffering. In recent years, high-intensity physical training, such as high-intensity cardiovascular training or strength training, has become increasingly popular in rehabilitation of many of these chronic diseases and disorders. However, the efficacy and safety of such high-intensity physical training in the prevention and treatment of chronic diseases and disorders still need to be explored.

In this special issue we invited researchers to contribute original research articles as well as review articles investigating the role of high-intensity physical training in the treatment of chronic diseases and disorders. A wide array of topics is discussed in this special issue, including (1) recovery after ACL reconstruction, (2) chronic kidney disease, (3) frail elderly, (4) hypertension, (5) inflammatory bowel disease, (6) degenerative spinocerebellar disease, (7) chronic pain in the neck and shoulders, (8) obesity, (9) cognitive impairment, (10) substance use disorder, and (11) cardiometabolic risk factors.

Our goal was to touch on different aspects of high-intensity physical training in the treatment of chronic diseases and disorders. We are delighted to see the outcome of the special issue and hope that it will inspire and stimulate further research in this area.


The editors of this special issue are indebted to all the authors who provided either original data or a comprehensive review of the previous and recent literature, making this special issue appealing to a diverse audience of researchers.

Lars L. Andersen

David G. Behm

Nicola A. Maffiuletti

Brad J. Schoenfeld