Research Article
The Biological Effects of Sex Hormones on Rabbit Articular Chondrocytes from Different Genders
Table 2
The expression of TIMP-3 and MMP-3 on different groups with analysis by RT-PCR.
| | Sex hormone | Expression of TIMP-3 (X-fold of control) | Expression of MMP-3 (X-fold of control) | | Male | Female | Male | Female |
| | Estradiol | | | | | | 10−6 () | 2.89 (2.68 to 3.11) | 22.41 **(20.99 to 23.83) | 0.31 (0.23 to 0.39) | 0.09 *(0.07 to 0.11) | | 10−7 () | 2.77 (2.62 to 2.92) | 13.68 **(9.54 to 17.42) | 0.24 (0.17 to 0.31) | 0.18 (0.13 to 0.23) | | Testosterone | | | | | | 10−6 () | 0.72 (0.69 to 0.75) | 3.21 (3.11 to 3.31) | 0.68 (0.56 to 0.81) | 0.17 (0.15 to 0.19) | | 10−7 () | 0.89 (0.78 to 1.01) | 3.31 (1.72 to 4.91) | 0.77 (0.50 to 1.04) | 0.18 (0.14 to 0.22) |
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Values are the mean (95% confidence interval [CI]).
: number of chondrocytes samples.
and by multiway ANOVA.
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