The K–Cl Cotransporter KCC3 as an Independent Prognostic Factor in Human Esophageal Squamous Cell Carcinoma

Table 3

Five-year survival rate of patients with esophageal cancer according to various clinicopathological parameters.

Variables	5-year survival; rate (%)	𝑃 value
Age
<60 years	53.13	0.1179
≥60 years	72.2
Gender
Male	65.35	0.8597
Female	68.57
Location of the primary tumor
Ut-Mt	73.63	0.0564
Lt-Ae	50.82
Histological type
Well/moderately differentiated SCC	71.94	0.2301
Poorly differentiated SCC	53.43
Tumor size
<50 mm	68.68	0.2809
≥50 mm	59.52
Lymphatic invasion
Negative	78.4	0.0168^∗
Positive	54.78
Venous invasion
Negative	78.18	0.0169^∗
Positive	48.7
pT
pT1	82.22	0.0024^∗
pT2-3	50.68
pN
pN0	82.72	0.0029^∗
pN1-3	49.68
MT
Low	68.21	0.7838
High	60.56
CN
Low	70.48	0.4151
High	59.25
CN/MT
CN ≤ MT	76.74	0.1329
CN > MT	55.48
Invasive front
Negative	81.82	0.0887
Positive	57.07

Ut: upper thoracic esophagus; Mt: middle thoracic esophagus; Lt: lower thoracic esophagus; Ae: abdominal esophagus; SCC: squamous cell carcinoma; pT: pathological T stage; pN: pathological N stage; MT: main tumor; CN: cancer nest.
^∗𝑃<0.05: log-rank test.