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BioMed Research International
Volume 2014, Article ID 936970, 6 pages
Clinical Study

Nonkeratinised Squamous Metaplasia of the Urinary Bladder in Children: A Report of Case Experiences

1Pediatric Surgery Department, Children’s Hospital, Marii Konopnickiej Street 65, 05-092 Dziekanów Leśny, Poland
2Urology Department, Military Medical Institute, Szaserów Street 128, 04-349 Warsaw, Poland

Received 28 February 2014; Accepted 27 March 2014; Published 15 April 2014

Academic Editor: Christian Schwentner

Copyright © 2014 Beata Jurkiewicz and Tomasz Ząbkowski. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Squamous metaplasia refers to the pathological transformation of the urothelium leading to nonkeratinised stratified squamous metaplasia (N-KSM). Objective. To present our experiences in the diagnosis and treatment of N-KSM of the urinary bladder in children. Materials and Methods. In this study, we present our experiences in the diagnosis and treatment of N-KSM of the urinary bladder in children aged from 5 to 17 years. From 2005 to 2013, metaplasia was diagnosed in 119 patients. The reasons behind visiting the hospital were nonspecific intense pain in the abdomen, recurrent urinary tract infections, and urination disorders. The most common symptoms of urinary bladder dysfunction were pollakiuria and difficulties in initiating micturition and retention of urine (reduced detrusor muscle activity). Results. In 20/119 patients (16.8%), metaplasia was incidentally diagnosed during cystoscopy performed for other causes. The changes characteristic for squamous metaplasia were diagnosed—in all these patients, a biopsy was performed. In all 119 patients, a squamous metaplasia was histopathologically diagnosed. Conclusions. Squamous metaplasia of the urinary bladder mucosa occurs in children and adolescents. Symptomatic treatment is administered mainly to improve the patients’ quality of life and disease prognosis.