Research Article

Immobilization of Murine Anti-BMP-2 Monoclonal Antibody on Various Biomaterials for Bone Tissue Engineering

Figure 4

Representative SEM photomicrographs of scaffolds prior to implantation (-) or with immobilized murine anti-BMP-2 retrieved 24 hours after implantation into rat critical-sized calvarial defects. Significant cellular infiltration and adhesion were observed on scaffolds immobilized with murine anti-BMP-2 mAb. Both alginate and ACS scaffolds had porous structure while the spheroidal Ti microbeads had an average diameter of 250 μm.
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