948264.fig.004a
(a)
948264.fig.004b
(b)
Figure 4: Kaplan-Meier curves ((a) overall survival and beta-catenin expression; (b) disease free survival and beta-catenin expression). Survival estimates have shown that OSCCS/OPSCCs overexpressing beta-catenin (cut-off >60%) are characterized by a worse prognosis, in terms of overall survival ( ; survival median of 28 months in high expressing tumors versus 66 months in low expressing OSCCs/OPSCCs) (a) and disease-free survival, with a more evident tendency to relapse and metastasis ( ; survival median of 20 months in high expressing tumors versus 30 months in low expressing OSCCs/OPSCCs) (b).