Human Serum Albumin Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN38) for Cancer Treatment

Figure 1

SN38-HSA synthesis scheme. The process consists of phenolic OH protection of SN38 (Compound 2), addition of glycine molecule (Compound 3), OH deprotection (Compound 4), succinyl addition (Compound 5), and HSA conjugation (Compound 6).