Human Serum Albumin Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN38) for Cancer Treatment

Table 3

Blood cell counts (RBC, WBC, and Hb) and biochemistry assays (AST, ALT enzymes, LDH, BUN, and Cr) in balb/c mice following 24 h treatment with SN38-HAS-15 versus control group. Values are presented as mean±SD (𝑛=3).

Assays	Sample	Control	SN38-HSA-15
Blood cell counts	WBC (1000/𝜇L)	3.3±0.611	3.1±1.83
	RBC (mil/uL)	10.1±1.40	9.8±1.71
	Hb (g/dL)	14.5±1.76	12.4±2.18
Biochemistry	AST (IU/L)	291±38.56	309.3±29.31
	ALT (IU/L)	56.2±6.08	53.6±3.76
	LDH (IU/L)	1052±97.52	1067±122.2
	BUN (mg/dL)	53.5±5.56	56.6±7.88
	Cr (mg/dL)	0.5±0.04	0.5±0.02