Liquiritigenin Induces Tumor Cell Death through Mitogen-Activated Protein Kinase- (MPAKs-) Mediated Pathway in Hepatocellular Carcinoma Cells
Figure 6
LQ inhibited PLC/PRF/5-xenografted tumor growth in BALB/c nude mice. Six BALB/c athymic nude mice inoculated with PLC/PRL/5 cells ( cells/mouse, i.p.) were treated with LQ (20 mg/kg, i.p., every other day) or vehicle solvent (0.9% saline solution, i.p., every other day) for 18 days. ((a), (b)) Tumor-possessing nude mice and tumor tissues separated from vehicle and LQ-treated groups. (c) Mean (S.D.) body weight of GA-treated and vehicle group (). (d) Tumor volumes were measured every other day. Tumor size in the curve was expressed as mean ± S.D. (). * and *** versus vehicle cells.
