In Silico Molecular Docking and In Vitro Antidiabetic Studies of Dihydropyrimido[4,5-a]acridin-2-amines

Table 7

% inhibition of α-glucosidase assay.

Concentration (μg/mL)	Acarbose	3a	3b	3c	3d	3e	3f
100	30.08±0.05	6.02±0.01	6.29±0.00	4.29±0.01	20.91±0.00	21.45±0.01^∗	14.02±0.02
200	45.02±0.12	8.32±0.01	7.31±0.02	5.02±0.01	21.65±0.01	24.62±0.09	10.77±0.03
300	68.25±0.21	10.12±0.01	8.01±0.03	6.09±0.02	22.71±0.02	56.85±0.01	15.85±0.04
400	78.01±0.07	11.45±0.02	8.25±0.06	9.19±0.02	23.01±0.04	60.25±0.01^∗∗	17.71±0.03

Values are mean ± SEM for groups of 3 observations.
^∗𝑃<0.01.
^∗∗𝑃<0.05.