Clinicopathological Factors Affecting Survival and Recurrence after Initial Hepatectomy in Non-B Non-C Hepatocellular Carcinoma Patients with Comparison to Hepatitis B or C Virus

Table 3

Lifestyle-related and preoperative clinical factors in Group NBNC according to alcohol consumption.

	NALP (𝑛=30)	ALP (𝑛=46)	𝑃 value
Age (years)	73.3 ± 6.3	69.7 ± 10.9	0.491
Gender (Male/Female)	22/8	45/1	0.001
Obesity	7 (23.3%)	8 (17.4%)	0.525
Hypertension	13 (43.3%)	23 (50.0%)	0.569
DM	11 (36.7%)	16 (34.8%)	0.867
Cigarette smoking	13 (43.3%)	34 (73.9%)	0.007
Albumin (g/dL)	3.7 (2.5–5.0)	3.9 (2.8–4.6)	0.658
Total Bilirubin (mg/dL)	0.5 (0.2–1.3)	0.5 (0.2–0.9)	0.834
Platelet count (×10^4/mm^3)	20.8 (8.0–40.4)	17.8 (6.7–51.6)	0.100
NLR	2.12 (0.87–12.80)	2.15 (0.79–7.43)	0.461
PT (%)	93.0 (54.8–131.4)	100.5 (63.4–131.4)	0.714
ICG R15 (%)	11.4 (0.3–29.0)	9.9 (1.6–31.5)	0.124
AFP (ng/mL)	7.0 (1–48157)	5.0 (1–7153)	0.398
DCP (mAU/mL)	94.0 (14–85330)	80.0 (11–15387)	0.741
Child-Pugh B/C	3 (10.0%)	3 (6.5%)	0.583
Multiple tumors	10 (33.3%)	12 (26.1%)	0.496
Tumor size (cm)	5.0 (1.0–15.0)	3.8 (1.2–17.0)	0.229
≧10 cm	6 (20.0%)	8 (17.4%)	0.774
BCLC stage B/C	9 (30.0%)	9 (19.6%)	0.296
Beyond Milan criteria	19 (63.3%)	19 (41.3%)	0.060
Preoperative TACE	15 (50.0%)	27 (58.7%)	0.456

NALP: non-alcoholic patients; ALP: alcoholic patients; DM: diabetes mellitus; NLR: neutrophil-to-lymphocyte ratio; PT: prothrombin time; ICG R15: indocyanine green retention rate at 15 minutes; AFP: serum 𝛼-fetoprotein; DCP: des-r-carboxyprothrombin; BCLC: Barcelona Clinic Liver Cancer; TACE: transcatheter arterial chemoembolization.