Determinants of Noninvasive Ventilation Outcomes during an Episode of Acute Hypercapnic Respiratory Failure in Chronic Obstructive Pulmonary Disease: The Effects of Comorbidities and Causes of Respiratory Failure

Table 1

Differences in the main demographic clinical and functional parameters between the two groups of patients. Values are expressed as mean ± standard deviation. SAPS: simplified acute physiology score, ABG: arterial blood gases, NIV: noninvasive ventilation, RICU: Respiratory Intensive Care Unit, LTOT: long term oxygen therapy, and HMV: home mechanical ventilation.

	42 NIV-failure	134 NIV-success	𝑃 value
Age (years)	81.05±7.05	77.81±9.27	0.019
Albumin (g/dL)	3.07±0.48	3.54±0.46	0.047
SAPS score	44.50±10.24	37.28±8.87	<0.001
Barthel score	7.95±9.37	15.86±17.77	<0.001
ABGs admission
P/F (PaO2/FiO2 ratio)	193±93.05	195±71.07	0.862
PaCO2 (mmHg)	73.60±23.64	79.93±19.27	0.080
pH	7.32±0.09	7.28±0.09	0.015
Days in hospital before RICU admission	9.21±13.93	4.59±8.79	0.047
LTOT	18/42	55/134	0.83
HMV	6/42	15/134	0.59