VEGF and eNOS Expression in Umbilical Cord from Pregnancy Complicated by Hypertensive Disorder with Different Severity
Table 2
Localization and immunostaining intensity of VEGF expression in umbilical cord tissue.
Control— (%)
GH— (%)
PE mild— (%)
PE severe— (%)
Amniotic epithelium
1+
0
65 (26)*
10 (4)*#
2+
45 (18)
30 (12)
58 (23)
45 (18)
3+
55 (22)
5 (2)
32 (13)
55 (22)
Wharton’s jelly
0
0
5 (2)*
0*
0
1+
32 (13)
85 (34)
75 (30)
55 (22
2+
38 (15)
10 (4)
25 (10)
28 (11)
3+
30 (12)
0
0
17 (7)
Artery endothelium
0
0
43 (17)*
40 (16)*
1+
68 (27)
57 (23)
60 (24)
100 (40)
2+
30 (12)
0
0
0
3+
2 (1)
0
0
0
Artery muscle cells
1+
65 (26)
100 (40)*
100 (40)*
83 (33
2+
35 (14)
0
0
17 (7)
Vein endothelium
0
0
50 (20)*
30 (12)*
1+
85 (34)
50 (20)
70 (28)
100 (40)
2+
15 (6)
0
0
0
Vein muscle cells
0
0
30 (12)*
18 (7)*
1+
80 (32)
70 (28)
82 (33)
80 (32)
2+
20 (8)
0
0
20 (8)
GH: gestational hypertension, PE: preeclampsia, : number of specimens, %: percentage.
*Significant = control versus GH, PE mild, PE severe. #Significant = GH versus PE mild, PE severe. Significant = PE mild versus severe.
