Research Article

Matrilin-2 Is a Widely Distributed Extracellular Matrix Protein and a Potential Biomarker in the Early Stage of Osteoarthritis in Articular Cartilage

Figure 2

Matrilin-2 expression in mouse dense connective tissues (DCT), loose connective tissues (LCT), and some specific epithelial cells: immunohistochemistry was performed by our unique domain-specific antibody. The localization of matrilin-2 protein was found in DCT, LCT, and some specific epithelial cells of a lot of organs. Immunostaining signal at least was detected in connective tissues of heart (a), colon (b), penis (c), esophagus (d), lung (e), kidney (f), and tracheal cartilage (g). We also found some specific epithelial cells strongly expressing matrilin-2 such as stomach (h) and duct epithelial cells of salivary gland (i). Bar, 200 μm.
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