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BioMed Research International
Volume 2015, Article ID 104912, 8 pages
http://dx.doi.org/10.1155/2015/104912
Review Article

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future

Department of Experimental Medicine, Istituto Pasteur Fondazione Cenci Bolognetti, Sapienza University, 00161 Rome, Italy

Received 28 February 2014; Accepted 29 October 2014

Academic Editor: Panayiotis Panayiotidis

Copyright © 2015 Marisa Granato et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Marisa Granato, Barbara Chiozzi, Maria Rosaria Filardi, Lavinia Vittoria Lotti, Livia Di Renzo, Alberto Faggioni, and Mara Cirone, “Tirosine kinase inhibitor tyrphostin AG490 triggers both apoptosis and autophagy by reducing HSF1 and Mcl-1 in PEL cells,” Cancer Letters, 2015. View at Publisher · View at Google Scholar
  • Marisa Granato, Maria Saveria Gilardini Montani, Mariarosari Filardi, Alberto Faggioni, and Mara Cirone, “Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression,” Oncotarget, vol. 6, no. 30, pp. 29543–29554, 2015. View at Publisher · View at Google Scholar
  • Marisa Granato, Celeste Rizzello, Maria Anele Romeo, Shivangi Yadav, Roberta Santarelli, Gabriella D’Orazi, Alberto Faggioni, and Mara Cirone, “Concomitant reduction of c-Myc expression and PI3K/AKT/mTOR signaling by quercetin induces a strong cytotoxic effect against Burkitt’s lymphoma,” The International Journal of Biochemistry & Cell Biology, vol. 79, pp. 393–400, 2016. View at Publisher · View at Google Scholar
  • Marisa Granato, Maria Saveria Gilardini Montani, Maria Anele Romeo, Roberta Santarelli, Roberta Gonnella, Gabriella D'Orazi, Alberto Faggioni, and Mara Cirone, “Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation,” Cellular Signalling, 2017. View at Publisher · View at Google Scholar
  • Marisa Granato, Celeste Rizzello, Maria Saveria Gilardini Montani, Laura Cuomo, Marina Vitillo, Roberta Santarelli, Roberta Gonnella, Gabriella D'Orazi, Alberto Faggioni, and Mara Cirone, “Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways,” The Journal of Nutritional Biochemistry, vol. 41, pp. 124–136, 2017. View at Publisher · View at Google Scholar
  • Marisa Granato, Maria Saveria Gilardini Montani, Roberta Santarelli, Gabriella D’Orazi, Alberto Faggioni, and Mara Cirone, “Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death,” Journal of Experimental & Clinical Cancer Research, vol. 36, no. 1, 2017. View at Publisher · View at Google Scholar