Review Article

MicroRNAs as Potential Biomarkers in Cancer: Opportunities and Challenges

Table 1

Types of specific miRNAs biomarkers in different cancers.

CancerType of biomarkermiRNAs biomarkersReference

Breast cancerDiagnosticmiR-10b, -21, -30a, -92a, -125b, -141, -145, -200, -801, -155, -191, -203, -210[112, 113]
PrognosticmiR-10b, -373, miR-210[43, 44]
PredictivemiR-125b[53]

Lung cancerDiagnosticmiR-21, -155, miR-16, miR-17, -19b, -25, -29c, -30c, -106a, -126, -451, -660, -28-3p[114ā€“116]
PrognosticmiR-221, let-7a, -137, miR-372, -182[41, 42]
miR-1, -15b, -16, -21, -126, -142-3p, -148a, -197[116]
PredictivemiR-128b[56]

Liver cancerDiagnosticmiR-222, -223, -181a, -181b, -181c, -200c, -203, -21, -224, -10b, -222, 126, -96[117, 118]
PrognosticmiR-21, -22, -26, -29, -31, -122, -124, -135a, -139, -145, -146a, -155, -200c, -221, -222, -222, -223[119]
PredictivemiR-21, -200b[52]

Colon cancerDiagnosticmiR-15b, -18a, -29a, -335, miR-17-3p, -20a, -21, -92, -601, -760, -29a[120, 121]
PrognosticmiR-141[122]
PredictivemiR-127-3p, -92a, -486-3p, -378, let-7g, miR-181b[54, 55]

Pancreatic cancerDiagnosticmiR-205, -21, miR-642b, -885-5p, -22[39, 123]
miR-145, -150, -223, -636, -26b, -34a, -122, -126*, -145, -150, -223, -505, -636, -885.5p[124]
PrognosticmiR-130b, miR-21, -105, -196a-2, -203, -210, -222, -452, -105, -127, -187, - 518a-2, - 30a-3p[125, 126]
PredictivemiR-21[52]

Prostate cancerDiagnosticmiR-30c, -622, -1285, miR-10b, -373, let-7c, -7e[43, 127]
miR-141, -375, miR-26a, -195[128]
PrognosticmiR-141, -375, miR-20a, -21, -141, -145, -221[45, 129]
PredictivemiR-21[130]

Ovarian cancerDiagnosticmiR-200 family, let-7 family, miR-21, -29a, -92, -93, miR-126, -127, -132, -155, -214, -182, -205, -144, -222, -302 [131ā€“133]
PrognosticmiR-410, -645, miR-200 family, miR-141, -429[46, 134]
PredictivemiR-23a, -27a, -30c, let-7g, -199a-3p, -181a, -181b, -213[132]