Aortic Arch Calcification Predicts the Renal Function Progression in Patients with Stage 3 to 5 Chronic Kidney Disease

Table 3

Determinants of aortic arch calcification in study patients (logistic regression).

	Univariate		Multivariate
	Odds ratio (95% CI)	value	Odds ratio (95% CI)	value
Age (per 1-year increase)	1.085 (1.058–1.114)	<0.0001	1.080 (1.048−1.111)	<0.0001
Male gender	0.737 (0.438–1.241)	0.252	—	—
Diabetes	1.533 (1.045–2.904)	0.001	0.821 (0.426−1.595)	0.575
BMI (per 1 m^2 increase)	1.071 (1.002–1.145)	0.042	0.993 (0.923−1.085)	0.875
UPCR (mg/g)	1.319 (0.741–2.346)	0.347	—	—
Baseline eGFR	0.989 (0.973–1.004)	0.144	—	—
CKD stage	1.196 (0.868–1.650)	0.274	—	—
eGFR slope	0.842 (0.777–0.911)	<0.0001	0.813 (0.773−0.938)	<0.0001
Calcium	1.036 (0.648–1.657)	0.882	—	—
Phosphorus	0.910 (0.676–1.226)	0.536	—	—
Ca × P	0.982 (0.951–1.013)	0.251	—	—
Albumin	0.770 (0.464–1.276)	0.310	—	—
Total cholesterol (mg/dL)	0.997 (0.993–1.002)	0.273	—	—
Triglyceride (mg/dL)	0.999 (0.997–1.002)	0.567	—	—
HDL	0.999 (0.980–1.019)	0.952	—	—
LDL	0.996 (0.989–1.002)	0.166	—	—
Cardiomegaly	3.911 (2.289–6.683)	<0.0001	2.491 (1.326−4.996)	0.010

BMI: body mass index; UPCR: urine protein-creatinine ratio; CKD: chronic kidney disease; eGFR: estimated glomerular filtration rate; HDL: high density lipoprotein cholesterol; LDL: low density lipoprotein cholesterol.