The Influence of Metabolic Factors for Nonalcoholic Fatty Liver Disease in Women
Table 1
Comparison of baseline characteristics in premenopausal women versus postmenopausal women.
Premenopausal women
Postmenopausal women
P
Number of subjects
728
695
<0.001
Age, years
46.9 ± 8.3
58.2 ± 6.7
<0.001
Body mass index, kg/m2
21.6 ± 2.7
22.6 ± 2.8
<0.001
Waist circumference, cm
78.7 ± 6.9
82.5 ± 7.4
<0.001
AST, IU/L
19.6 ± 6.7
22.9 ± 7.1
<0.001
ALT, IU/L
17.2 ± 9.9
21.8 ± 12.3
<0.001
GGT, IU/L
19.3 ± 14.7
24.3 ± 20.0
<0.001
Fasting glucose, mg/dL
90.5 ± 10.7
94.6 ± 14.9
<0.001
Triglycerides, mg/dL
84.4 ± 56.4
99.7 ± 59.4
<0.001
HDL-cholesterol, mg/dL
58.0 ± 13.2
51.0 ± 10.7
0.03
LDL-cholesterol, mg/dL
117.7 ± 27.9
128.4 ± 30.6
<0.001
CRP, mg/dL
0.08 ± 0.2
0.11 ± 0.24
0.019
HOMA
1.4 ± 1.0
1.6 ± 1.3
0.013
Smoking, %
2.8
2.2
0.291
Regular exercise, %
38.2
19.6
<0.001
Hypertension, %
17.2
36.2
<0.001
Diabetes, %
12.1
23.7
<0.001
Metabolic syndrome, %
8.8
25.9
<0.001
NAFLD, %
14.4
27.2
<0.001
Data are presented as the mean ± SD. P value by Student’s t-test for continuous variables and chi-square test for categorical variables. ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; HDL: high density lipoprotein; LDL: low density lipoprotein; CRP: C-reactive protein; HOMA: homeostasis model assessment-estimated insulin resistance; NAFLD: nonalcoholic fatty liver disease.
