The Influence of Metabolic Factors for Nonalcoholic Fatty Liver Disease in Women
Table 2
Comparison of baseline characteristics in postmenopausal women without NAFLD versus with NAFLD.
Postmenopausal women without NAFLD
Postmenopausal women with NAFLD
P
Number of subjects
506
189
Age, years
57.7 ± 6.6
59.6 ± 6.7
<0.001
Body mass index, kg/m2
21.9 ± 2.3
24.5 ± 2.9
<0.001
Waist circumference, cm
80.8 ± 6.8
86.9 ± 7.0
<0.001
AST, IU/L
22.3 ± 5.8
24.6 ± 9.4
<0.001
ALT, IU/L
19.3 ± 8.9
28.3 ± 17.0
<0.001
GGT, IU/L
21.9 ± 17.3
30.9 ± 24.8
<0.001
Fasting glucose, mg/dL
92.1 ± 11.0
101.5 ± 20.5
<0.001
Triglycerides, mg/dL
86.7 ± 46.0
134.4 ± 75.4
<0.001
HDL-cholesterol, mg/dL
60.7 ± 12.0
54.0 ± 10.3
<0.001
LDL-cholesterol, mg/dL
127.6 ± 30.3
130.4 ± 31.3
0.216
CRP, mg/dL
0.09 ± 0.2
0.16 ± 0.28
0.006
HOMA
1.4 ± 1.2
2.2 ± 1.4
<0.001
Smoking, %
2.2
2.2
0.616
Regular exercise, %
17.4
25.9
0.012
Hypertension, %
30.1
52.4
<0.001
Diabetes, %
16.7
42.3
<0.001
Metabolic syndrome, %
16.8
50.3
<0.001
Hormone therapy
10.9%
6.3%
0.045
Data are presented as the mean ± SD. P value by Student’s t-test for continuous variables and chi-square test for categorical variables. ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; HDL: high density lipoprotein; LDL: low density lipoprotein; CRP: C-reactive protein; HOMA: homeostasis model assessment-estimated insulin resistance; NAFLD: nonalcoholic fatty liver disease.
