The Influence of Metabolic Factors for Nonalcoholic Fatty Liver Disease in Women

Table 6

Unadjusted and adjusted analyses for the risk of NAFLD in premenopausal women.

	Unadjusted OR (95% CI)	P	Adjusted OR (95% CI)	P
Age	1.03 (0.99–1.06)	0.124	1.04 (0.99–1.10)	0.121
Hypertension	2.68 (1.73–4.17)	<0.001	1.57 (0.69–3.55)	0.283
Diabetes	3.57 (2.22–5.74)	<0.001	2.07 (0.77–5.53)	0.149
Triglyceridemia	5.57 (3.09–10.03)	<0.001	1.75 (0.62–5.00)	0.293
HDL	0.46 (0.29–0.75)	0.002	0.36 (0.16–0.83)	0.016
Central obesity	4.91 (3.10–7.76)	<0.001	2.79 (1.25–6.24)	0.012
Smoking	0.78 (0.21–2.89)	0.713	0.70 (0.08–6.14)	0.744
Exercise	1.59 (0.96–2.62)	0.072	1.70 (0.79–3.66)	0.176
ALT	1.07 (1.04–1.10)	<0.001	1.06 (1.02–1.10)	0.003
GGT	1.01 (1.00–1.02)	0.022	1.01 (0.99–1.03)	0.475
HOMA	1.72 (1.37–2.16)	<0.001	2.46 (1.51–4.00)	<0.001

NAFLD: nonalcoholic fatty liver disease; ALT: alanine aminotransferase; GGT: gamma-glutamyl transpeptidase; OR: odds ratio; CI: confidence interval; HDL: high density lipoprotein; HOMA: homeostasis model assessment-estimated insulin resistance.