Results from the Registry of Atrial Fibrillation (AFABE): Gap between Undiagnosed and Registered Atrial Fibrillation in Adults—Ineffectiveness of Oral Anticoagulation Treatment with VKA

Table 2

AF prevalence, TTR, and average CHA₂DS₂VAS_C and HAS-BLED scores stratified by age.

	60–64	65–69	70–74	75–79	80–84	>85	Total/mean
All ()	9840	9690	7993	7146	6864	6792	48325
Men	4918	4756	3868	3331	2870	2543	22286; (46.1%)
Women	4922	4934	4125	3815	3994	4249	26039; (53.8%)
Registered cases
Prevalence of AF
	185	300	441	687	932	1093	3638
(%)	(1.88)	(3.09)	(5.51)	(9.61)	(13.57)	(16.09)	(7.5%; CI = 95%, 7.29–7.76)
Men							1950 (53.6%)
Women							1688 (46.4%)
Expected cases (AFABE)
Prevalence of AF
	236	329	871	1000	1345	1657	5268
(%)	(2.4)	(3.4)	(10.9)	(14.0)	(19.6)	(24.4)	(10.9%; CI = 95%, 9.1–12.8)
Absolute difference	−51	−29	−430	−313	−413	−564	−1630; (30.9%; CI = 95%, 28.6–32.2)
Average CHA2DS2VASC score	3.3%	8.9%	12.6%	24.5%	29.4%	21.2%
(AFABE)	1.22	2.20	2.76	3.92	4.06	4.07	3.60; (CI = 95%, 3.41–3.79)
HAS-BLED ≥ 3 (%)	1.12%	14.6%	13.48%	24.71%	29.21%	16.85%	47.6%; (CI = 95%, 45.7–49.48)
Total AF and no OAC (%)	27.5%; (21.6–33.4)	15.8%; (11.7–19.9)	51.2%; (47.8–54.5)	32.8%; (29.8–35.9)	31.9%; (29.4–34.5)	36.1%; (33.8–38.4)	31.04%; (CI = 95%, 29.7–32.3)
TTR ≥ 60%	66.2	65.3	69.1	66.3	68.1	66.7	67.03%; (CI = 95%, 65.2–68.8)
SAME-TT2R2 ≥2
	63	111	181	321	451	591	1805
(%)	(36.8%)	(40.0%)	(44.2%)	(49.1%)	(50.4%)	(57.6%)	50.5% (CI = 95%, 48.9–52.2)
Registered prevalence of stroke and AF
	18	39	46	103	140	219	565
(%)	(9.7%)	(13%)	(10.4%)	(14.9%)	(15.0%)	(20.0%)	15.53% (CI = 95%, 14.3–16.7)
Registered AF incidence/1000/year
	28	40	67	83	90	130
/1000/year	2.8	4.1	8.4	11.6	13.1	19.1	438
CI = 95%	(1.9–4.1)	(2.9–5.6)	(6.5–0.6)	(9.3–14.4)	(10.5–16.1)	(16.0–22.7)	9.1 (CI = 95%, 8.2–10.0)