BioMed Research International
Volume 2015, Article ID 139451, 10 pages
http://dx.doi.org/10.1155/2015/139451
Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice
1Edmond H. Fischer Signal Transduction Laboratory, School of Life Sciences, Jilin University, Changchun 130012, China
2Academy of Traditional Chinese Medicine and Chinese Medicinal Materials of Jilin Province, Changchun 130012, China
3Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
4Department of Colorectal and Anal Surgery, The Second Hospital, Jilin University, Changchun 130041, China
Received 2 February 2015; Revised 14 April 2015; Accepted 23 April 2015
Academic Editor: Julian Weghuber
Copyright © 2015 Jing Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Supplementary Material
The Supplementary Materials involve 4 figures of the quantitative analysis of magnolol and honokiol in ME by HPLC-MS/MS，Effects of ME on Akt，Effect of ME alone on IR, and The effect of ME on body weight of mice, thanks to the reviewer’s constructive suggestion to further illustrate the components and functions of ME.