Pan-Genome Analysis of Human Gastric Pathogen <i>H. pylori</i>: Comparative Genomics and Pathogenomics Approaches to Identify Regions Associated with Pathogenicity and Prediction of Potential Core Therapeutic Targets

<div>Whole genome/proteome pairwise alignment and comparative analysis. The translated genomes of all<i> H. pylori </i>available strains are analyzed by BLASTp analysis. Pairwise comparisons across<i> H. pylori </i>proteomes are plotted in blast matrix. The shared proteome between any two<i> H. pylori </i>genomes and the percentage of similarities is calculated and shown in corresponding boxes, where the color intensity indicated the similarity. The diagonal row of rectangular boxes in the matrix illustrates the internal homology against its own proteome.</div>

BioMed Research International

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Figure 2: Pan-Genome Analysis of Human Gastric Pathogen <i>H. pylori</i>: Comparative Genomics and Pathogenomics Approaches to Identify Regions Associated with Pathogenicity and Prediction of Potential Core Therapeutic Targets 

Figure 2 | Pan-Genome Analysis of Human Gastric Pathogen H. pylori: Comparative Genomics and Pathogenomics Approaches to Identify Regions Associated with Pathogenicity and Prediction of Potential Core Therapeutic Targets 