Ameliorative Effect of Zinc Oxide Nanoparticles on Antioxidants and Sperm Characteristics in Streptozotocin-Induced Diabetic Rat Testes

Table 4

Effect of zinc oxide nanoparticles on the mRNA expression profile (fold of change relative to the control group) of antioxidant genes in streptozotocin-induced diabetic rat testes.

Genes	Control	Diabetic	Diabetic + ZnONPs	Diabetic + ZnONPs + insulin
SOD	1 ± 0.01	0.15 ± 0.02	0.99 ± 0.09	1.12 ± 0.15
CAT	1.07 ± 0.02	0.22 ± 0.02	1.04 ± 0.02	1.7 ± 0.25
GPx	1.06 ± 0.02	0.30 ± 0.09	1.06 ± 0.02	3.3 ± 0.87
GR	1.05 ± 0.03	0.29 ± 0.08	1.4 ± 0.26	4 ± 0.6
GST	0.94 ± 0.03	0.13 ± 0.02	1.06 ± 0.03	1.76 ± 0.4

Each point represents the mean ±  from triplicate determinations ( rats per group). Means within the same row carrying different superscripts (a, b, and c) are significant at .