1,25-Dihydroxyvitamin D<sub><b>3</b></sub> Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPAR<svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-4.15277pt" id="M1" height="11.9949pt" version="1.1" viewBox="0 -7.84213 8.73445 11.9949" width="8.73445pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g14-225" d="M509 371C509 424 479 457 448 457C426 457 396 430 396 412C396 402 399 390 403 385C408 379 419 356 419 332C419 273 339 136 289 80H287C293 136 294 245 280 332C266 417 238 457 195 457C148 457 86 420 22 324L54 291C97 339 115 347 125 347C134 347 139 344 148 321C184 230 198 65 182 -18C151 -78 117 -167 109 -219L127 -242C168 -239 248 -212 273 -197C267 -162 262 -93 262 -21C267 -12 277 2 322 58C439 202 509 289 509 371Z"/></g></svg> Signaling Pathway

<div>The iNOS, MR, VDR, and PPAR<i>γ</i> immunofluorescence expression after VDR siRNA intervention (200x).</div>

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fig10

Figure 10

Figure 10: 1,25-Dihydroxyvitamin D<sub><b>3</b></sub> Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPAR<svg xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-4.15277pt" id="M1" height="11.9949pt" version="1.1" viewBox="0 -7.84213 8.73445 11.9949" width="8.73445pt"><g transform="matrix(.017,0,0,-0.017,0,0)"><path id="g14-225" d="M509 371C509 424 479 457 448 457C426 457 396 430 396 412C396 402 399 390 403 385C408 379 419 356 419 332C419 273 339 136 289 80H287C293 136 294 245 280 332C266 417 238 457 195 457C148 457 86 420 22 324L54 291C97 339 115 347 125 347C134 347 139 344 148 321C184 230 198 65 182 -18C151 -78 117 -167 109 -219L127 -242C168 -239 248 -212 273 -197C267 -162 262 -93 262 -21C267 -12 277 2 322 58C439 202 509 289 509 371Z"/></g></svg> Signaling Pathway 

BioMed Research International

1,25-Dihydroxyvitamin D3 Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPAR Signaling Pathway

Figure 10

1,25-Dihydroxyvitamin D₃ Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPAR Signaling Pathway