HFE Genotyping in Patients with Elevated Serum Iron Indices and Liver Diseases

Figure 1

Biochemical iron markers and relationship with HFE genotype. Higher levels of transferrin saturation were observed in the HFE-HH genotype when compared to other HFE genotypes and wild type (96.71% versus 71.75%, , and 96.71% versus 75.44%, , resp.). Significant differences were also observed among serum iron levels (221 μg/dL, 192 μg/dL and 178 μg/dL, resp., ). Nonsignificant differences in ferritin levels were observed between HFE-HH genotype group, and other HFE genotypes and wild type (3323.50 ng/mL, 1246.5 ng/mL, and 1354.5 ng/mL, resp., ). Furthermore, nonsignificant differences regarding the median of transferrin levels in each group were observed (200 mg/dL, 220 mg/dL, and 190 mg/dL, resp., ).