Effect of Clinoptilolite and Sepiolite Nanoclays on Human and Parasitic Highly Phagocytic Cells

Figure 3

Uptake of nanoclays by amoebas and macrophages. TEM of 5 μm thickness cross section of amoebas (a–c) and human macrophages (d–f) nontreated (a) and (d) or treated with clinoptilolite NC (b) and (e) or sepiolite NC (c) and (f). Dashed arrows are showing the cytosolic membrane of amoebas and macrophages. Black arrows are showing the vacuolar membrane, many of them containing high accumulation of clinoptilolite and sepiolite NC. Red arrow shows a possible vacuolar membrane rupture for sepiolite NC accumulation. The green and pink arrows show the accumulation of clinoptilolite and sepiolite NC in macrophages, respectively.

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