Figure 1: Morphological features of Caco-2 cells after 24 h treatment with RFRA (R. fairholmianus root acetone) extract. There were no significant visible differences in both control and 0.5% DMSO treated cells (a and b). The RFRA extract treated cells (c, d, e, and f) after 24 h showed loss of intact membrane, loss of contact with neighbouring cells, condensed and detached from the culture plate.