Characterizing Spatial Dynamics of Bifurcation to Alternans in Isolated Whole Rabbit Hearts Based on Alternate Pacing

Figure 1

Schematic of the alternate pacing protocol for a specific BCL . Grey boxes indicate responses that have been captured during optical mapping experiments. Local onset of alternans was calculated based on steady state (SS) responses at , while alternans induced by perturbations was calculated based on responses captured at increasing values.