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BioMed Research International
Volume 2015, Article ID 172165, 12 pages
Research Article

Diagnostic Significance of Diffusion-Weighted MRI in Renal Cancer

Department of Emergency, The First Affiliated Hospital of Jilin University, Changchun, Jilin 130021, China

Received 28 August 2014; Accepted 16 January 2015

Academic Editor: Paul L. Crispen

Copyright © 2015 Yu Lei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. This study aimed to investigate whether diffusion-weighted imaging (DWI) could contribute to the discrimination between benign and malignant renal cancer. Methods. We searched the PubMed electronic database for eligible studies. STATA 12.0 software was used for statistical analysis. The SMD and 95% CI were calculated. Results. Decreased ADC signal was seen in all renal cancer patients (cancer tissue versus normal tissue: SMD = 1.63 and 95% CI = 0.96~2.29, ; cancer tissue versus benign tissue: SMD = 2.22 and 95% CI = 1.53~2.90 and , resp.). MRI machine type-stratified analysis showed that decreased ADC signal was found by all included MRI machine types in cancer tissues compared with benign cancer tissues (all ). The ADC values of renal cancer patients were significantly lower than those of normal controls for all included values (all ), and there was a decreased ADC signal at -500, -600, -1000, -500, and 1000 gradients compared with benign cancer tissues (all ). Conclusion. Our study concluded that decreased ADC signal presented in DWI may be essential for the differential diagnosis of renal cancer.