Omega-3 Fatty Acids in Early Prevention of Inflammatory Neurodegenerative Disease: A Focus on Alzheimer’s Disease

Figure 1

Schematic representation showing key pathological features of the degenerative process in Alzheimer’s disease (AD). The common characteristics are (1) amyloid-β plaques and (2) neurofibrillary tangles. Neuroinflammatory changes (3) have been identified as the third important component of the disease. Microglia migrate to the plaques and enhance amyloid-β deposition with chronic activation. Brain and neuron images from Wikimedia Commons (http://upload.wikimedia.org/wikipedia/commons/c/cc/Alzheimers_brain.jpg. http://upload.wikimedia.org/wikipedia/commons/b/be/Derived_Neuron_schema_with_no_labels.svg).