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BioMed Research International
Volume 2015 (2015), Article ID 174732, 9 pages
http://dx.doi.org/10.1155/2015/174732
Research Article

Genetic Diversity of Mycobacterium tuberculosis Complex Isolated from Tuberculosis Patients in Bahir Dar City and Its Surroundings, Northwest Ethiopia

1Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia
2Faculty of Veterinary Medicine, University of Gondar, P.O. Box 346, Gondar, Ethiopia
3College of Veterinary Medicine and Agriculture, Addis Ababa University, P.O. Box 34, Debre Zeit, Ethiopia
4Bahir Dar Regional Health Research Laboratory Centre, P.O. Box 641, Bahir Dar, Ethiopia
5J. Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD, USA

Received 20 June 2015; Revised 8 August 2015; Accepted 17 August 2015

Academic Editor: Isabel Portugal

Copyright © 2015 Anwar Nuru et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. WHO, Global Tuberculosis Report, WHO, Geneva, Switzerland, 2014.
  2. Federal Ministry of Health, Guidelines for Clinical and Programmatic Management of TB, Leprosy and TB/HIV in Ethiopia, Federal Ministry of Health, Addis Ababa, Ethiopia, 15th edition, 2012.
  3. R. Firdessa, S. Berg, E. Hailu et al., “Mycobacterial lineages causing pulmonary and extrapulmonary Tuberculosis, Ethiopia,” Emerging Infectious Diseases, vol. 19, no. 3, pp. 460–463, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. WHO, Global Tuberculosis Report, WHO, Geneva, Switzerland, 2011.
  5. D. García De Viedma, I. Mokrousov, and N. Rastogi, “Innovations in the molecular epidemiology of tuberculosis,” Enfermedades Infecciosas y Microbiología Clínica, vol. 29, no. 1, pp. 8–13, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Brudey, J. R. Driscoll, L. Rigouts et al., “Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology,” BMC Microbiology, vol. 6, article 23, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. Central Statistics Agency, Summary and Statistical Report of the 2007 Population and Housing Census: Population Size by Age and Sex, Central Statistics Agency, Addis Ababa, Ethiopia, 2007.
  8. M. Ali, “Status of homeless population in urban Ethiopia: a case study of Amhara region,” International Journal of Management and Social Sciences Research, vol. 3, no. 1, pp. 61–68, 2014. View at Google Scholar
  9. C. W. Schmidt, “Linking TB and the environment: an overlooked mitigation strategy,” Environmental Health Perspectives, vol. 116, no. 11, pp. A478–A485, 2008. View at Publisher · View at Google Scholar
  10. Federal Ministry of Health, Tuberculosis, Leprosy and TB/HIV Prevention and Control Programme, Federal Ministry of Health, Addis Ababa, Ethiopia, 4th edition, 2008.
  11. WHO, Laboratory Services in Tuberculosis Control: Culture. Part III, World Health Organization (WHO), Geneva, Switzerland, 1998.
  12. J. Kamerbeek, L. Schouls, A. Kolk et al., “Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology,” Journal of Clinical Microbiology, vol. 35, no. 4, pp. 907–914, 1997. View at Google Scholar · View at Scopus
  13. StataCorp LP, Stata Statistical Software: Release 12, StataCorp LP, College Station, Tex, USA, 2011.
  14. B. Tessema, J. Beer, M. Merker et al., “Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia,” BMC Infectious Diseases, vol. 13, no. 1, article 131, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. M. Belay, G. Ameni, G. Bjune, D. Couvin, N. Rastogi, and F. Abebe, “Strain diversity of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in afar pastoral region of Ethiopia,” BioMed Research International, vol. 2014, Article ID 238532, 12 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Mihret, Y. Bekele, M. Aytenew et al., “Modern lineages of Mycobacterium tuberculosis in Addis Ababa, Ethiopia: implications for the tuberculosis control programe,” African Journal of Health Sciences, vol. 12, no. 3, pp. 339–344, 2012. View at Publisher · View at Google Scholar · View at Scopus
  17. L. Garedew, A. Mihret, G. Mamo et al., “Strain diversity of mycobacteria isolated from pulmonary tuberculosis patients at Debre Birhan Hospital, Ethiopia,” International Journal of Tuberculosis and Lung Disease, vol. 17, no. 8, pp. 1076–1081, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Debebe, A. Admassu, G. Mamo, and G. Ameni, “Molecular characterization of Mycobacterium tuberculosis isolated from pulmonary tuberculosis patients in Felege Hiwot Referral Hospital, northwest Ethiopia,” Journal of Microbiology, Immunology and Infection, vol. 47, no. 4, pp. 333–338, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. S. Godreuil, F. Renaud, M. Choisy et al., “Highly structured genetic diversity of the Mycobacterium tuberculosis population in Djibouti,” Clinical Microbiology and Infection, vol. 16, no. 7, pp. 1023–1026, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Bruchfeld, G. Aderaye, I. B. Palme et al., “Molecular epidemiology and drug resistance of Mycobacterium tuberculosis isolates from ethiopian pulmonary tuberculosis patients with and without human immunodeficiency virus infection,” Journal of Clinical Microbiology, vol. 40, no. 5, pp. 1636–1643, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. B. Diriba, T. Berkessa, G. Mamo, Y. Tedla, and G. Ameni, “Spoligotyping of multidrug-resistant Mycobacterium tuberculosis isolates in Ethiopia,” International Journal of Tuberculosis and Lung Disease, vol. 17, no. 2, pp. 246–250, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Verver, R. M. Warren, Z. Munch et al., “Transmission of tuberculosis in a high incidence urban community in South Africa,” International Journal of Epidemiology, vol. 33, no. 2, pp. 351–357, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. J. R. Glynn, A. C. Crampin, M. D. Yates et al., “The importance of recent infection with Mycobacterium tuberculosis in an area with high HIV prevalence: a long-term molecular epidemiological study in Northern Malawi,” Journal of Infectious Diseases, vol. 192, no. 3, pp. 480–487, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. P. J. Easterbrook, A. Gibson, S. Murad et al., “High rates of clustering of strains causing tuberculosis in Harare, Zimbabwe: a molecular epidemiological study,” Journal of Clinical Microbiology, vol. 42, no. 10, pp. 4536–4544, 2004. View at Publisher · View at Google Scholar
  25. C. Demay, B. Liens, T. Burguière et al., “SITVITWEB—a publicly available international multimarker database for studying Mycobacterium tuberculosis genetic diversity and molecular epidemiology,” Infection, Genetics and Evolution, vol. 12, no. 4, pp. 755–766, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. I. C. Shamputa, L. Rigouts, L. A. Eyongeta et al., “Genotypic and phenotypic heterogeneity among Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients,” Journal of Clinical Microbiology, vol. 42, no. 12, pp. 5528–5536, 2004. View at Publisher · View at Google Scholar
  27. O. Lahlou, J. Millet, I. Chaoui et al., “The genotypic population structure of Mycobacterium tuberculosis complex from Moroccan patients reveals a predominance of Euro-American lineages,” PLoS ONE, vol. 7, no. 10, Article ID e47113, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. S. Gagneux, “Host-pathogen coevolution in human tuberculosis,” Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 367, no. 1590, pp. 850–859, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Coscolla and S. Gagneux, “Consequences of genomic diversity in Mycobacterium tuberculosis,” Seminars in Immunology, vol. 26, no. 6, pp. 431–444, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. F. Cruciani, P. Santolamazza, P. Shen et al., “A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes,” American Journal of Human Genetics, vol. 70, no. 5, pp. 1197–1214, 2002. View at Publisher · View at Google Scholar · View at Scopus